Job Description Summary
Seeking highly motivated individuals for a postdoctoral position in neuropathology and neuroimmunology for projects that encompasses both basic and translational research.
Aberrant immune activity after brain injury during prenatal life affects critical phases of brain development, with long-lasting behavioral abnormalities relevant to neurodevelopmental disorders. The complement system is a central effector mechanism of innate and adaptive immunity. It is involved in essential neurobiological functions related to brain development, including synaptic remodeling, neuronal migration, and response to brain insults. Our studies have revealed a central role for complement in recognizing injured neurons/synapses and promoting their engulfment by microglia. These postdoctoral projects investigate the mechanisms of a complement-mediated secondary immune response in the developing brain following neo/prenatal brain injury.
Studies utilize different mouse models of mild and severe pediatric brain injury. The projects will involve advanced microscopy, cellular and molecular immune profile analysis, high dimensional analyses, detailed assessments of mouse behavioral studies, and the development of novel therapeutic approaches. This postdoctoral research program will be supervised by Dr. Onder Albayram, Ph.D. from the Department of Pathology and Laboratory Medicine, and Dr. Stephen Tomlinson, Ph.D. from the Department of Immunology and Microbiology, both of whom can provide exposure and training in the newly linked neuro and immune disciplines. Successful candidates will have strong communications skills and a PhD and/or MD in a suitable discipline of biochemistry, molecular biology, immunology, physiology, or neuroscience.Entity
Medical University of South Carolina (MUSC - Univ)Worker Type
EmployeeWorker Sub-Type?
RegularCost Center
CC000981 COM M&I Operations CCPay Rate Type
SalaryPay Grade
University-00Scheduled Weekly Hours
40Work Shift
Job Description
Job Duties:
Lead a project related to above described work, perform experimental procedures from list above. 35%
Analysis and interpretation of data. 35%
Assist with projects of other lab personnel in related projects when required. Duties could include those listed in Job Summary. 15%
Keep records and up to date lab notebook. Write manuscripts. Review literature. 15%
Preferred Experience & Additional Skills: A PhD degree in biology or other natural, life or health care science related to the assigned area of research. Preferably at least one year postdoctoral experience.
Minimum Experience and Training Requirements: Ph.D. or M.D./Ph.D.
Physical Requirements:
(Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift)
Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent)
Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required
Additional Job Description
Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
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