Job Description Summary
Candidate will lead a team using mouse model systems to develop novel therapeutics for diseases involving fibrosis for which there are currently no effective, FDA-approved treatments. The candidate will perform supervised work on several projects using animal models of fibrosis. General duties will include processing and analyzing tissue samples from mice, performing various biologic analyses (gel electrophoresis, Western blotting, immunohistochemistry, etc.), and participating in laboratory discussions, organization and regulatory procedures. Maintenance of up-to-date, comprehensive and neat laboratory records will be required.
Under supervision from the principal investigator, candidate will perform complex biological procedures and analyses in a basic science laboratory. All of the experiments require meticulous technique and the ability to optimize and troubleshoot a variety of different protocols. The candidate will be expected to help prepare experimental results for presentation and publication. The candidate will also be expected to provide guidance to other staff working on the project.
Will require occasional weekend work.Entity
Medical University of South Carolina (MUSC - Univ)Worker Type
EmployeeWorker Sub-Type?
Research GrantCost Center
CC000975 COM DOM Rheumatology CCPay Rate Type
SalaryPay Grade
University-00
Pay Range
$0 - $0 - $0Scheduled Weekly Hours
40Work Shift
Job Description
Job Duties:
35% - Conducts studies on the efficacy in a variety of animal model systems of novel therapeutic agents developed in our lab. Expertise in mouse handling, surgery, immunological and histological methods, fluorescent microscopy, and evaluation of organ function, and evaluation of organ function are a must.
25% - Maintain laboratory notebook/ computer files of samples/ data, conduct analyses, draft figures and tables.
15% - Present experimental data in laboratory meetings and participate in presentations of journal club and research conferences.
15% - Order supplies, maintain laboratory to meet criteria for institutional standards of safety and
biohazard considerations.
10% - Perform and analyze studies involving single cell and/or single nucleus RNA Seq.
Knowledge, Skills, and Abilities Preferred:
- Knowledge about cell, molecular, biochemical, and/or immunological methods is essential, and experience in these areas is desired. The candidate should possess strong organizational and communication skills, a talent for managing diverse tasks, and an ability to work well in a team.
- Candidate should be highly motivated, detail oriented, and committed to excellence. The ideal candidate will have a keen intellectual interest in the science behind the projects and a demonstrated commitment to increasing their background knowledge about their work. An equivalent combination of education and experience may substitute for stated requirements.
Additional Job Description
MUSC Minimum Training and Experience Requirements:
A Ph.D., M.D. or equivalent with two years post doctorate experience.
Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent)
Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
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