Job Description Summary
A senior staff scientist is sought to assist a well-funded neuroscience research lab with analysis of epigenetic and transcriptional regulatory factors involved in behaviors associated with autism spectrum disorders or substance and alcohol use disorders. The successful applicant will have extensive experience with experimental approaches to studying chromatin state, epigenetic regulation of gene expression, and modern transcriptomic analysis of single cells. The applicant must be independent and highly motivated and have demonstrated ability to work well in a research team. Ideal candidate will have a PhD, postdoctoral experience, and experience as a staff scientist, and will have co-authored peer-reviewed original research publications related to epigenetics and genomics.Entity
Medical University of South Carolina (MUSC - Univ)Worker Type
EmployeeWorker Sub-Type?
Research GrantCost Center
CC000984 COM NEURO RES Operations CCPay Rate Type
SalaryPay Grade
University-00
Pay Range
$0 - $0 - $0Scheduled Weekly Hours
40Work Shift
Job Description
Job Duties:
• 35%: Carry out original research projects to advance goals of funded research projects. This includes performing biochemical and in silico experiments to evaluate chromatin state produced by epigenetic enzymes or transcription factors, performing experiments to assess binding of epigenetic enzymes to genomic DNA, analysis of changes in gene expression using qRT-PCR, RNA scope, or single-cell sequencing approaches. Additional original research likely involves working with lab animals (mice) to extract brain tissues, performing survival surgeries on mice for behavior or molecular-genetic analyses.
• 25%: Assist the PI with generation of extramural grant proposals and peer-reviewed publications, including the generation of publication-quality figures, detailed experimental methods write-ups, and assistance with manuscript preparation.
• 15%: Interpret data and report on work in progress at weekly meetings.
- 15%: Supervise and mentor lab volunteers or graduate students, and train new lab members in techniques as needed.
- 10%: Assist the lab director with generating figures and text for research publications.
Minimum Requirements: Ph.D., M.D. or equivalent with seven years postdoctorate experience
Additional Job Description
Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent)
Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
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